Faculty-Run Labs
Read about the exciting research areas pursued by our 37 faculty-run labs.
Altman Lab (Helix Group)
We use informatics, data science and AI to understand how drugs work, how we can discover new drugs and how we can use drugs alone and in combination to create new therapeutic strategies.
Boahen Lab (Brains in Silicon)
We're emulating the brainin silicon by reverse-engineering the computing brain, linking the fields of electrical engineering and computer science with neurobiology and medicine.
Camarillo Lab
We design devices to precisely measure and control motion/forces in the brain, heart, lung, and reproductive system. Our interests span sensors, machine learning, robotics, biomechanics and pathophysiology.
Coleman Lab
The Coleman Neural Interaction Lab focuses on the interactions between multiple neural systems using an intersection of disciplines including neuroscience, data science, and technology.
Delp Lab
Delp (Neuromuscular Biomechanics) Lab uses our expertise in biomechanics, computer science, imaging, robotics, and neuroscience to analyze muscle function, study human movement, design medical technologies, and optimize human performance.
Fordyce Lab
We develop new microfluidic technologies for high-throughput and quantitative biochemistry and biophysics. With these platforms, we probe how molecular sequence dictates function with the goal of understanding how mutations drive disease and how we can design molecules with new functions.
Hill-Maini Lab
We integrate synthetic biology, biochemistry, and gastronomy to unlock the potential of fungi for sustainability. We study filamentous fungi which not only serve global roles in nutrient cycling and agriculture, but have immense potential for sustainable foods, chemicals, and materials.
Jewett Lab
Our lab advances synthetic biology research in support of planet and societal health. We develop methods to elucidate principles about how the living world works, to create cell-free biotechnologies for transforming bioengineering applications in health, manufacturing, sustainability, and education.
Liphardt Lab
We're a team of physicists, engineers, and biologists. We investigate the organization and dynamics of single molecules in living cells using new optical tools. In these studies, we collect time-series data and then analyze them to find underlying regulatory and organizational principles.
Nuyujukian Lab
Brain Interfacing Laboratory's research mission is to understanding causal relationships between multidimensional cortical dynamics and behavior, improving the diagnosis and treatment of brain-related disorders such as stroke and epilepsy, and establishing brain-machine interfaces as a platform technology for neurological disorders.
Quake Lab
Our research is concerned with developing new approaches to biological measurement and applying these approaches to problems of both fundamental and medical interest.
Swartz Lab
Our program focuses on human health as well as planet health. We seek to synergistically combine: 1) the design and evolution of complex protein-based nanoparticles and enzymatic systems with 2) innovative, uniquely capable cell-free production technologies.
Yang Group
Our mission is to develop therapeutics for regenerating human tissues and treating diseases such as musculoskeletal diseases, cardiovascular diseases, and cancer. We develop biomaterials for forming 3D artificial cell niche to promote stem cell differentiation and tissue regeneration.
Barron Lab
We focus on biomimicry of natural host defense peptides (LL-37) and investigate its role in Alzheimer’s dementia. We also develop biostable peptoid mimics of LL-37 as therapeutics that can combat antibiotic-resistant infections.
Brophy Lab
Our goal is to use genetic engineering to build a sustainable future. We are developing synthetic genetic circuit tools that enable precise control over gene expression for a variety of plants.
Chiu Lab
We develop experimental and computational methodology for cryo-electron microscopy and tomography and their applications to a broad spectrum of biological systems from molecules to cells essential to understand various biological processes.
Covert Lab
Our lab invents new technologies related to systems biology to better measure, analyze, and model the behaviors of individual cells. Our biological focus is in host-pathogen interactions and our technological foci are whole-cell modeling and live-cell imaging.
Endy Lab
Our work expand the boundaries of synthetic biology, by advancing reusable bio-measurements and materials, developing tools for whole-cell measurement and modeling. We support policy work in bio-safety, security, economy, equity, and justice.
Garten Lab
Garten Lab studies how parasites interface with host cells, at which we can exploit these mechanisms not only to develop cures for parasitic diseases but also to engineer host's cells. Our research aims to transforms parasites from agents of disease to tools for health.
KC Huang Lab
Our lab is driven to understand how cells determine their shape, form, and physiological state. We are inspired by the beauty of mechanism - discovery of how biological systems integrate physics, chemistry, and mathematics to achieve functions that manifest only in living matter.
Lee Lab
We're interested in understanding how the brain works at the systems level. We seek to understand the connectivity and function of these large-scale networks in order to drive the development of new therapies for neurological diseases.
Lundberg Lab
We study how human proteins are distributed in time and space, and how variations in localization modulate dynamic cell functions and how mislocalization gives rise to disease. We work at the intersection of bioimaging, proteomics and artificial intelligence.
Prakash Lab
We are a curiosity driven lab that seeks to understand how computation is embodied in biological matter including study of non-model organisms. We are dedicated towards inventing, building and scaling-up “frugal science” tools to democratize access to science.
Skylar-Scott Lab
We develop new integrative biofabrication methods towards the goal of whole-organ engineering. Our main focus is on building heart and vascular tissues to provide new therapies for children born with congenital heart defects
HR Thiam Lab
We investigate the biophysical mechanisms of innate immune cell functions to develop new tools to manipulate and measure intra- and extra-cellular forces. We harness these biophysical mechanisms to re-engineer immune cells for improved performance in physically challenging environments as seen in vivo.
Bintu Lab
We use systems and synthetic biology approaches to characterize the dynamics of gene and chromatin regulation in mammalian cells. Our goal is to build a quantitative and predictive framework to improve mammalian cell engineering.
Bryant Lab
Molecular motors lie at the heart of biological processes ranging from DNA replication to cell migration. We seek to understand the inner workings of these nanoscale machines.
Cochran Lab
We use combinatorial and rational methods to engineer designer protein therapeutics for applications in regenerative medicine and oncology. We also develop new technologies for high-throughput protein analysis and engineering.
Deisseroth Lab
Our lab develops high-resolution tools to control and map elements in biological systems to study neural physiology and behavior in mammals. Our interests include neural circuit dynamics in behavior and neuropsychiatric symptoms and treatments.
Fischbach Group
Our lab studies microbiome-host interactions. Our approach is based on two technologies we developed: a complex (119-member) defined gut community, and new genetic systems for common species from the microbiome.
Hernández-López Lab
Our group works at the interface of synthetic biology and systems biology for understanding and reprogramming biomedical relevant cellular behaviors. We are currently interested in immune cellular therapies against cancer and neurodegeneration.
Possu Huang Lab
We develop protein modeling AI tools and molecular platforms for biomedical applications. We're interested in protein structural dynamics, enzyme function, and molecular assembly, using design to conduct scientific investigation.
Lin Lab
We engineer proteins for remote control and sensing of biology in living animals. Our work includes fast fluorescent voltage indicators for visualizing electrical activity in the brain and molecular devices for detecting and treating cancer.
Marsden Lab
Marsden (Cardiovascular Biomechanics Computation) Lab develops fundamental computational methods for studying cardiovascular disease progression, surgical methods, treatment planning, and medical devices. We focus on patient-specific modeling in pediatric and congenital heart disease, as well as adult cardiovascular disease.
Qi Lab
We combine CRISPR genome engineering, molecular engineering, synthetic biology, and bioinformatics to study human genomics, as well as to develop novel gene therapy and cell therapy to treat cancer, degeneration, and infectious diseases.
Soh Lab
We develop biosensor systems that can measure biomolecules for early disease detection and targeted treatments. Our laboratory develops synthetic reagents that can perform useful molecular functions that conventional antibodies cannot and we also develop advanced electronic and optical hardware to fabricate the biosensors.
Wang Lab
We integrate functional genomic analysis, novel microscopy, and physical models to study whole-body regeneration, the ability to regenerate all body parts.