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A multiplex ELISA based diagnostics for COVID19

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(August 2020)

Why: Ramp up on PCR based COVID-19 tests has allowed for limited testing availability, but serological based new tests are needed rapidly at scale. This is also true considering conditions in Lower Middle Income Countries (LMICs).

Project plan:

With progress on recombinant expression of viral proteins and ongoing work in Peter Kim Lab and BioHub on developing ELISA reagents, we are rapidly putting together an automated modular diagnostics platform to conduct a multi-plex low-cost micro-spotting based ELISA test compatible with Octopi based scanning/imaging platform. This complimentary approach will be useful for surveillance as well as diagnostics.

Relevant Publications or More Information

Collaborators:

• Manu Prakash (Bioengineering)

• Peter Kim (Biochemistry)

• CZ BioHub

• Shalin Mehta Lab (BioHub)